Current Projects

The lab is focused on studying the role of chromatin structure in a diverse group of processes that happen on the molecule of DNA.The model organisms are human, yeast and flies. Research of chromatin structure, mainly at its higher levels of compaction, encompasses a large number of contemporary Molecular Biology techniques aiming at building a clearer picture of the role chromatin and its organization have on gene expression, DNA repair and recombination.

The lab is currently involved in five major projects:


Investigation of the ecological pressure in the Bulgarian Black sea aquatory  using the Black sea mussel Mytilus galloprovincialis Lam as a model through integrated microbiological, biochemical and molecular biology markers
2018 - 2021 - № КП-06-Н21/7
Research project sponsored by the Bulgarian Science Fund

A field detector for genotoxicity from CBRN and explosive devices
2017 - 2020 - SPS MYP G5266
This project is sponsored by NATO Science for Peace and Security Programme

Chromatin structure and dynamics during the lifespan of living organisms – elucidating the most intricate mechanisms that govern cellular fate
2017 - 2020 - DH 11-15
Research project sponsored by the Bulgarian Science Fund

Natural Deep Eutectic Solvents (NADES)
2017 - 2020 - DH 19-4
Research project sponsored by the Bulgarian Science Fund

Novel Nitrogen Heterocyclic Luminophores Capable of Intramolecular Proton Transfer and Their Metal Complexes for Modern Biomedicine

2017 - 2020 - DH 19-11
Research project sponsored by the Bulgarian Science Fund

Molecular mechanisms of immune tolerance - importance for endocrine function of regulatory T-cells  
2016 - 2019 - DH 03-4
Research project sponsored by the Bulgarian Science Fund



Work is in progress and graduate students, MSc and PhD students, and post-docs with interests in the expanding field of Epigenetics and its multivariate applications in human life and health could contact Prof. Miloshev via email:

miloshev@bio21.bas.bg;  
gmlab@chromatinepigenetics.com


The following projects have been and some are still under execution at the laboratory:
Research is sponsored fully by the Bulgarian Science Fund, Grant number DMU 02/8

Research is sponsored fully by the Bulgarian Science Fund, Grant number DVU 02/61

Research is sponsored fully by the Bulgarian Science Fund, Grant number DID 02/35

Research is sponsored fully by the Youth In Action Program, Grant number BG13/A1.2/242/R2