Current Projects

The lab is focused on studying the role of chromatin structure in a diverse group of processes that happen on the molecule of DNA.The model organisms are human, yeast and flies. Research of chromatin structure, mainly at its higher levels of compaction, encompasses a large number of contemporary Molecular Biology techniques aiming at building a clearer picture of the role chromatin and its organization have on gene expression, DNA repair and recombination.

The lab is currently involved in five major projects:


1.  A field detector for genotoxicity from CBRN and explosive devices

2017 - 2020 - SPS MYP G5266
This project is sponsored by NATO Science for Peace and Security Programme

 2. Molecular mechanisms of immune tolerance - importance for endocrine function of regulatory T-cells  

 2016 - 2019 - DH 03-4
Research project sponsored by the Bulgarian Science Fund

3. Chromatin structure and dynamics during the lifespan of living organisms – elucidating the most intricate mechanisms that govern cellular fate


4. Genetic and epigenetic based research of ageing and age-associated human diseases


5. Advancement and application of modern methods for biomonitoring of the environment 

Work is in progress and graduate students, MSc and PhD students, and post-docs with interests in the expanding field of Epigenetics and its multivariate applications in human life and health could contact Prof. Miloshev via email:
miloshev@bio21.bas.bg;  
gmlab@chromatinepigenetics.com

The following projects have been and some are still under execution at the laboratory:
Research is sponsored fully by the Bulgarian Science Fund, Grant number DMU 02/8

Research is sponsored fully by the Bulgarian Science Fund, Grant number DVU 02/61

Research is sponsored fully by the Bulgarian Science Fund, Grant number DID 02/35

Research is sponsored fully by the Youth In Action Program, Grant number BG13/A1.2/242/R2